NUR 641E WK1 DQ2 Discussion

NUR 641E WK1 DQ2 Discussion

Topic 1 DQ 2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style. The the condition that I choose in the first discussion question was an allergic reaction. This is what was written: An allergic condition is an inflammatory process that alters the body\’s immune system when exposed to an allergen (Marshall et al., 2018). The body\’s immune system produces immunoglobulin E (IgE) antibody that binds acting as a white blood cell into the bloodstream. In early allergic exposure, the pathophysiologic reaction responds immediately after the allergen is exposed to the body\’s immune system, and inflammatory mediators that comprise significant quantities of histamine are directly released from mast cells on the mucosal surfaces. Also, histamine causes rapid bronchospasm and bronchoconstriction. This narrows the bronchioles in the case of an allergic patient. It is essential to give allergic patient education to detect early the signs and symptoms of food-induced to allergic reactions. Thus, the patient will be aware of food supplements that bring the condition and manage the condition NUR 641E WK1 DQ2 Discussion


Week 1 DQ2

An allergic reaction is a serious condition that occurs when the body’s immune system detects a foreign substance in the body as harmful. Cetrizine is a medication that can be used to treat this condition. Cetirizine, an antihistamine medication, is a metabolite of hydroxyzine. Its key effects are mediated by selective activation of intrinsic H1 receptors. The antihistamine function of cetirizine has been indicated in a number of human and animal models (Nagvi and Gerriets, 2019). In vivo as well as ex vivo animal approaches demonstrated antiserotonergic and anticholinergic effects. Even so, in clinical trials, dry breath was identified to be more common with cetirizine more than a placebo. In vitro binding site tests have shown no detectable sensitivity of cetirizine to histamine receptors besides H1 receptors. NUR 641E WK1 DQ2 Discussion

Cetirizine has adverse side-effects and can be life-threatening if not monitored appropriately. Common side effects include dry mouth, stomach upset, tiredness, drowsiness, diarrhea, and vomiting (Jordakieva,et al.,2020). Certain side effects of cetirizine may arise that do not normally require medical attention. Such side effects may disappear away during therapy as the body responds to the drug. A health care provider will also be able to advise whether to avoid or minimize some of the side effects. Cetirizine has not shown much effect on pregnant women hence it is not harmful to them.

A baseline assessment should be completed that includes any presence of allergens. A complete medication evaluation to prevent furthering the effects, Education should be provided to the patient and any caregivers. This education should include the correct administration of the drug, signs, and symptoms of both hyper and hypomagnesemia, and when to notify the physician. The desired outcome will be a reduction in the allergic condition within a defined range for the patient.


Jordakieva, G., Kundi, M., Lemell, P., Zieglmayer, R., Zieglmayer, P., Jensen-Jarolim, E., & Crevenna, R. (2020). Cetirizine inhibits gender-specific blood cell dynamics upon allergen contact in allergic rhinitis. Clinical Immunology, 108422.

Naqvi, A., & Gerriets, V. (2019). Cetirizine. In StatPearls [Internet]. StatPearls Publishing.  NUR 641E WK1 DQ2 Discussion