Discussion – Psoriasis and Breast Tumors

Your initial post should be at least 300 words, formatted, and cited in proper current APA style with support from at least 2 academic sources. Your initial post is worth 8 points.

You should respond to at least two of your peers by extending, refuting/correcting, or adding additional nuance to their posts. Your reply posts are worth 2 points (1 point per response.)Discussion – Psoriasis and Breast Tumors

All replies must be constructive and use literature where possible.

This discussion contains 2 parts:

• KM is a 38-year-old white woman with a 6-year history of psoriasis. Her family history includes allergies and asthma and her mother with psoriasis. KM returns today for an increase in symptoms, and she wants to improve the appearance of her skin. Please discuss the following:
• What is the underlying cause of psoriasis?
• What are the common signs and symptoms of this disease?
• Define, Compare and Contrast the following conditions:
• Fibrocystic breast disease
• Fibroadenoma
• Malignant breast tumor

Submission Instructions:

Your initial post should be at least 300 words, formatted and cited in proper current APA style with support from at least 2 academic sources. Your initial post is worth 8 points.

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You should respond to at least two of your peers by extending, refuting/correcting, or adding additional nuance to their posts. Your reply posts are worth 2 points (1 point per response.)

All replies must be constructive and use literature where possible.

Part 1-Psoriasis- Causes, Signs and Symptoms

Psoriasis is a chronic dermatological inflammatory disease which involves hyper-proliferation of basal cells of the skin and subsequent increased turnover of epidermal cells. Genetic, immunologic and environmental factors play a role in the development of psoriasis. Through an auto immunological process, the immune system causes inflammation of the basal cells, which triggers new skin cells to hyper-proliferate. Usually, the replacement of skin cells occurs every 10-30days. With psoriasis, the turnover occurs every 3 to 4 days. The increased turnover causes a buildup of old cells. The replacement of old cells with new ones creates white and silver scales. A rare gene mutation known as CARD14, which is inheritable within a family, has a linkage with psoriasis development and can be inherited within a family (Rendon & Schäkel, 2019). The gene plays a role in the creation of plaque psoriasis. Discussion – Psoriasis and Breast Tumors

According to Rendon & Schäkel (2019), environmental factors include microbial skin infections, diet, chemical irritants, and UV radiation exposure. The disease commonly manifests on the skin of lumbosacral areas, elbows, knees, scalp, glans penis and inter-gluteal clefts. This disease’s common signs and symptoms include pruritus, many small scaly areas of skin, conjunctivitis or blepharitis, and joint pain. Plaque psoriasis, raised roughened with a white scale with underlying erythema, can occur at the most common sites.

Part 2-Breast Tumors- Definition, Comparison and Contrast

Fibrocystic breast disease is a condition which gives the barest a lumpy texture and is the most common breast mass among women. Fibro-adenomas are uncancerous breast tumors that are the most prevalent among women aged 30 years and below. Fibro adenomas have a 9% prevalence of all solid breast masses in women younger than 19 years old. Malignant breast tumor is a cancerous breast mass, which can occur in the epithelium, ducts and lobules. Fibro adenomas and fibrocystic breast disease are non-cancerous. Malignant breast tumor can invade nearby tissues. Fibroadenoma and fibrocystic breast disease are caused by hormonal changes, which affect breast tissue (Li et al., 2018).  Malignant breast tumors are caused by several factors like gene mutations, exposure to radiation, or hematogenous spread from other body parts.

References

Li, Z., Yu, L., Wang, X., Yu, H., Gao, Y., Ren, Y., & Zhou, X. (2018). Diagnostic performance of mammographic texture analysis in the differential diagnosis of benign and malignant breast tumors. Clinical breast cancer, 18(4), e621-e627.

Rendon, A., & Schäkel, K. (2019). Psoriasis Pathogenesis and Treatment. International journal of molecular sciences, 20(6), 1475. https://doi.org/10.3390/ijms20061475 Discussion – Psoriasis and Breast Tumors