Clinical Practice Guideline Essay

Clinical Practice Guideline Essay

The selected topic is Clostridium difficile infection (CDI) in adults. CDI is characterized by diarrhea and colitis. CDI is confirmed by either a positive stool test or detection of toxicity of Clostridium difficile (McDonald et al., 2018). Additionally, histopathologic or colonoscopy findings indicating pseudomembranous colitis, show the presence of CDI. CDI has become a serious health problem as evidenced by its increased incidence and severity. Therefore, prevention, correct diagnosis, and effective treatment of CDIs are essential to lower the risk for patients, reduce the spread of the infection, and also eliminate the likelihood of recurrent infections (Kukla et al., 2020). Therefore, guidelines are developed to guide the diagnosis, management, and treatment of CDI. The guidelines normally systematize the latest evidence and data and integrate the latest changes to guide the management and treatment of CDI. Clinical Practice Guideline Essay.

The following clinical guidelines for the management of CDI were identified:

·         Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)


·         Updates in the Management of Clostridium difficile for Adults (2019)

·         2019 update of the WSES guidelines for the management of Clostridioides (Clostridium) difficile infection in surgical patients


It was interesting to discover from the guidelines that the risk factors for the CDI include being older than 65 years, the use of antibiotics, recent hospitalization, and weak immunity. Severe cases of CDI can cause toxic megacolon, sepsis, and multiple organ failure (Sartelli et al., 2019). Spores causing CDI spread through the fecal-oral route, airborne environmental dispersal within hospitals, and hand-to-hand contact. The guidelines recommend that patients presenting with unexplained watery stools within 24 hours to have the stools tested for CDI. Currently, the first-line treatment options for severe and non-severe initial incidents of CDI include oral vancomycin and fidaxomicin (Ng, 2019). Clinical Practice Guideline Essay.



Kukla, M., Adrych, K., Dobrowolska, A., Mach, T., Reguła, J., & Rydzewska, G. (2020). Guidelines for Clostridium difficile infection in adults. Przeglad gastroenterologiczny, 15(1), 1–21.


McDonald, L. C., Gerding, D. N., Johnson, S., Bakken, J. S., Carroll, K. C., Coffin, S. E., … & Loo, V. (2018). Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clinical Infectious Diseases, 66(7), e1-e48.

Ng, K. (2019). Updates in the Management of Clostridium difficile for Adults.

Sartelli, M., Di Bella, S., McFarland, L. V., Khanna, S., Furuya-Kanamori, L., Abuzeid, N., … & Ben-Ishay, O. (2019). 2019 update of the WSES guidelines for the management of Clostridioides (Clostridium) difficile infection in surgical patients. World journal of emergency surgery, 14(1), 1-29. Clinical Practice Guideline Essay.

Purpose: To expose you to clinical practice guidelines. Clinical practice guidelines (CPG) are “systematically developed statements to assist practitioner decisions about appropriate health care for specific clinical circumstances.” Guidelines can be used to reduce inappropriate variations in practice and to promote the delivery of high quality, evidence-based health care. They may also provide a mechanism by which healthcare professionals can be made accountable for clinical activities. Although most of the development and evaluation of CPG has occurred in the field of medicine, nurses are becoming more interested in the use of guidelines as one means of facilitating evidence-based practice.  Thomas L Clinical practice guidelines Evidence-Based Nursing 1999;2:38-39

Tasks: Search online for clinical practice guidelines applicable to your BSN nursing practice problem you are interested in during this semester.

What topic did you look for within the CPG? Was it difficult to find? What did the CPG say that you did not know?

What sites did you find? List at three (3) not listed below.

Other sites you may find are as follows:

    •  Guideline Summaries (Links to an external site.)
    • American Association of Neuroscience Nurses  (Links to an external site.)
    • National Guidelines Clearinghouse  (Links to an external site.)
    • Emergency Nurses Association  (Links to an external site.)
    • Registered Nurse Association of Ontario (Links to an external site.)

Have you used any of the guidelines before?

Initial response due Saturday @ 11:59 pm

Respond to two (2) others due by Monday @ 11 am

Clinical Practice Guideline Essay